Academic career
| 1995.4-1999.3 | PhD. Graduate School of Medicine, Kyoto University
|
| 1999.4-2001.2 | Postdoctral Fellow, Osaka University
|
| 2001.3-2005.4 | Postdoctral Fellow, Baylor College of Medicine
|
| 2005.5- | Assistant Professor, Institute for Chemical Resarch, Kyoto University |
Research field
Current research
- A study of chemicals which alter the cell differentiation
- A study of small organic molecules which regulate gene recombination
Selected publications
- Kwon Y, Arndt HD, Mao Q, Choi Y, Kawazoe Y, Dervan PB, Uesugi M., Small molecule transcription factor mimic J Am Chem Soc 126, 15940-15941 (2004) [pubmed]
- Kawazoe Y, Tanaka S, Uesugi M., Chemical genetic identification of the histamine H1 receptoras astimulator of insulin-induced adipogenesis Chem Biol. 11, 907-913 (2004) [pubmed]
- Shimogawa H, Kwon Y, Mao Q, Kawazoe Y, Choi Y, Asada S, Kigoshi H, Uesugi M., A wrench-shaped synthetic moleculethat modulates a transcription factor-coactivator interaction J Am Chem Soc 24, 3461-3471 (2004) [pubmed]
- Choi Y, Kawazoe Y, Murakami K, Misawa H, Uesugi M., Identification of bioactive moleculesby adipogenesis profiling of organic compounds J Biol Chem. 278, 7320-7324 (2003) [pubmed]
- Naka T, Tsutsui H, Fujimoto M, Kawazoe Y, Kohzaki H, Morita Y, Nakagawa R, Narazaki M, Adachi K, Yoshimoto T, Nakanishi K, Kishimoto T., SOCS-1/SSI-1-deficient NKT cells participate in severe hepatitis through dysregulated cross-talk inhibition of IFN-gamma and IL-4 signaling in vivo Immunity 14, 535-545 (2001) [pubmed]
- Kawazoe Y, Naka T, Fujimoto M, Kohzaki H, Morita Y, Narazaki M, Okumura K, Saitoh H, Nakagawa R, Uchiyama Y, Akira S, Kishimoto T., Signal transducer and activator of transcription (STAT)-induced STAT inhibitor 1 (SSI-1)/suppressor of cytokine signaling 1 (SOCS1) inhibits insulin signal transduction pathway through modulating insulin receptor substrate 1 (IRS-1) phosphorylation J Exp Med. 193, 263-269 (2001) [pubmed]
- Fujimoto M, Naka T, Nakagawa R, Kawazoe Y, Morita Y, Tateishi A, Okumura K, Narazaki M, Kishimoto T., Defective thymocyte development and perturbed homeostasis of T cells in STAT-induced STAT inhibitor-1/suppressors of cytokine signaling-1 transgenic mice J Immunol. 165, 1799-1806 (2000) [pubmed]
- Morita Y, Naka T, Kawazoe Y, Fujimoto M, Narazaki M, Nakagawa R, Fukuyama H, Nagata S, Kishimoto T., Signals transducers and activators of transcription (STAT)-induced STAT inhibitor-1 (SSI-1)/suppressor of cytokine signaling-1 (SOCS-1) suppresses tumor necrosis factor alpha-induced cell death in fibroblasts Proc Natl Acad Sci U S A. 97, 5405-5410 (2000) [pubmed]
- Kawazoe Y, Tanabe M, Sasai N, Nagata K, Nakai A., HSF3 is a major heat shock responsive factor duringchicken embryonic development Eur J Biochem. 265, 688-697 (1999) [pubmed]
- Kawazoe Y, Tanabe M, Nakai A., Ubiquitous and cell-specific members of the avian small heat shock protein family FEBS Lett. 455, 271-275 (1999) [pubmed]
- Kawazoe Y, Nakai A, Tanabe M, Nagata K., Proteasome inhibition leads to the activation of all members of the heat-shock-factor family Eur J Biochem. 255, 356-362 (1998) [pubmed]
- Tanabe M, Kawazoe Y, Takeda S, Morimoto RI, Nagata K, Nakai A., Disruption of the HSF3 gene results in the severe reduction of heat shock gene expression and loss of thermotolerance EMBO J. 17, 1750-1758 (1998) [pubmed]
- Tanabe M, Nakai A, Kawazoe Y, Nagata K., Different thresholds in the responses of two heat shock transcription factors, HSF1 and HSF3 J Biol Chem. 272, 15389-15395 (1997) [pubmed]
- Nakai A, Tanabe M, Kawazoe Y, Inazawa J, Morimoto RI, Nagata K., HSF4, a new member of the human heat shock factor family which lacks properties of a transcriptional activator Mol Cell Biol. 17, 469-481 (1997) [pubmed]
- Nakai A, Kawazoe Y, Tanabe M, Nagata K, Morimoto RI., The DNA-binding properties of two heat shock factors, HSF1 and HSF3, are induced in the avian erythroblast cell line HD6 Mol Cell Biol. 15, 5268-5278 (1995) [pubmed]
|