京都大学化学研究所研究者情報   [ English | Japanese ]


金久　實（かねひさ　みのる）

バイオインフォマティクスセンター 化学生命科学
（理学研究科生物科学専攻・薬学研究科医薬創成情報科学専攻 協力講座）
教授
理学博士（東京大学）
URL:http://kanehisa.kuicr.kyoto-u.ac.jp/index_J.html
E-mail: kanehisa@kuicr.kyoto-u.ac.jp
Tel: 0774-38-3270
Fax: 0774-38-3269
研究・教育歴
    1975.3 東京大学大学院理学系研究科博士課程修了
    1976.2 東京大学理学博士
    1976.3〜1985.9 米国ジョンズホプキンス大学研究員、ロスアラモス国立研究所研究員、国立衛生研究所（NIH）主任研究員
    1985.10〜1987.6 京都大学化学研究所助教授
    1987.7〜 京都大学化学研究所教授
    1991.7〜1995.6, 2002.7〜 東京大学医科学研究所教授（併任）
    2005.1〜 ボストン大学客員教授
専門分野
    生命情報学
主な研究テーマ
  1. 創薬・医療・環境保全のためのバイオインフォマティクス技術開発
  2. ゲノムとケミストリーの融合解析による生命システムの機能解読
  3. 生命システム情報統合データベース（KEGG）の開発
主な論文・著書
  1. Moriya, Y., Shigemizu, D., Hattori, M., Tokimatsu, T., Kotera, M., Goto, S., and Kanehisa, M., PathPred: an enzyme-catalyzed metabolic pathway prediction server. Nucleic Acids Res. 38, W138-W143 (2010)  [pubmed]
  2. Kanehisa, M., Goto, S., Furumichi, M., Tanabe, M., and Hirakawa, M., KEGG for representation and analysis of molecular networks involving diseases and drugs. Nucleic Acids Res. 38, D355-D360 (2010)  [pubmed]
  3. Shigemizu, D., Araki, M., Okuda, S., Goto, S., and Kanehisa, M., Extraction and analysis of chemical modification patterns in drug development. J Chem Inf Model 49, 1122-9 (2009)  [pubmed]
  4. Hashimoto, K., Tokimatsu, T., Kawano, S., Yoshizawa, A.C., Okuda, S., Goto, S., and Kanehisa, M., Comprehensive analysis of glycosyltransferases in eukaryotic genomes for structural and functional characterization of glycans. Carbohydr Res 344, 881-7 (2009)  [pubmed]
  5. Yamanishi, Y., Araki, M., Gutteridge, A., Honda, W., and Kanehisa, M., Prediction of drug-target interaction networks from the integration of chemical and genomic spaces. Bioinformatics 24, i232-i240 (2008).  [pubmed]
  6. Kanehisa, M., Araki, M., Goto, S., Hattori, M., Hirakawa, M., Itoh, M., Katayama, T., Kawashima, S., Okuda, S., Tokimatsu, T., and Yamanishi, Y., KEGG for linking genomes to life and the environment. Nucleic Acids Res. 36, D480-D484 (2008).  [pubmed]
  7. Hashimoto, K., Yoshizawa, A.C., Okuda, S., Kuma, K., Goto, S., and Kanehisa, M., The repertoire of desaturases and elongases reveals fatty acid variations in 56 eukaryotic genomes. J. Lipid Res. 49, 183-191 (2008).  [pubmed]
  8. Limviphuvadh, V., Tanaka, S., Goto, S., Ueda, K., and Kanehisa, M., The commonality of protein interaction networks determined in Neurodegenerative disorders (NDDs). Bioinformatics 23, 2129-2138 (2007).  [pubmed]
  9. Oh, M., Yamada, T., Hattori, M., Goto, S., and Kanehisa, M., Systematic analysis of enzyme-catalyzed reaction patterns and prediction of microbial biodegradation pathways. J. Chem. Inf. Model. 47, 1702-1712 (2007).  [pubmed]
  10. Minowa, Y., Araki, M., and Kanehisa, M., Comprehensive analysis of distinctive polyketide and nonribosomal peptide structural motifs encoded in microbial genomes. J. Mol. Biol. 368, 1500-1517 (2007).  [pubmed]
  11. Hashimoto, K., Goto, S., Kawano, S., Aoki-Kinoshita, K.F., Ueda, N., Hamajima, M., Kawasaki, T., and Kanehisa, M., KEGG as a glycome informatics resource. Glycobiology 16, 63R-70R (2006).  [pubmed]
  12. Kanehisa, M., Goto, S., Hattori, M., Aoki-Kinoshita, K.F., Itoh, M., Kawashima, S., Katayama, T., Araki, M., and Hirakawa, M., From genomics to chemical genomics: new developments in KEGG. Nucleic Acids Res. 34, D354-D357 (2006).  [pubmed]
  13. Kawano, S., Hashimoto, K., Miyama, T., Goto, S., and Kanehisa, M., Prediction of glycan structures from gene expression data based on glycosyltransferase reactions. Bioinformatics 21, 3976-3982 (2005).  [pubmed]
  14. Yamanishi, Y., Vert, J.-P., and Kanehisa, M., Supervised enzyme network inference from the integration of genomic data and chemical information. Bioinformatics 21, i468-i477 (2005).  [pubmed]
  15. Kotera, M., Okuno, Y., Hattori, M., Goto, S., and Kanehisa, M., Computational assignment of the EC numbers for genomic-scale analysis of enzymatic reactions. J. Am. Chem. Soc. 126, 16487-16498 (2004).  [pubmed]
  16. Igarashi, Y., Aoki, K.F., Mamitsuka, H., Kuma, K., and Kanehisa, M., The evolutionary repertoires of the eukaryotic-type ABC transporters in terms of the phylogeny of ATP-binding domains in eukaryotes and prokaryotes. Mol. Biol. Evol. 21, 2149-2160 (2004).  [pubmed]
  17. Hattori, M., Okuno, Y., Goto, S., and Kanehisa, M., Development of a chemical structure comparison method for integrated analysis of chemical and genomic information in the metabolic pathways. J. Am. Chem. Soc. 125, 11853-11856 (2003).  [pubmed]
  18. Kanehisa, M. and Bork, P., Bioinformatics in the post-sequence era. Nature Genetics 33, 305-310 (2003).  [pubmed]
  19. Kanehisa, M., "Post-genome Informatcs" Oxford University Press, Oxford (2000)

Update: Aug 03,2012