Faculty Information, Institute for Chemical Research, Kyoto University   [ English | Japanese ]


KANEHISA, Minoru

Bioinformatics Center - Chemical Life Science -
（Laboratory in the Graduate School of Science and Graduate School of Pharmaceutical Sciences）
Professor
D.Sc., University of Tokyo
URL:http://kanehisa.kuicr.kyoto-u.ac.jp/
E-mail: kanehisa@kuicr.kyoto-u.ac.jp
Tel: 0774-38-3270
Fax: 0774-38-3269
Academic career
    1975.3 Graduated from Dr. Course, University of Tokyo
    1976.2 D.Sc., University of Tokyo
    1976.3-1985.9 Johns Hopkins University School of Medicine, Los Alamos National Laboratory, National Institutes of Health
    1985.10-1987.6 Associate Professor, Kyoto University, Institute for Chemical Research
    1987.7- Professor, Kyoto University, Institute for Chemical Research
    1991.7-1995.6, 2002.7- Professor (concurrent), University of Tokyo, Institute of Medical Science
    2005.1- Visiting Professor, Boston University
Research field
    Bioinformatics
Current research
  1. New bioinformatics technologies for pharmaceutical, medical, and environmental sciences
  2. Deciphering systemic biological functions by integrated analysis of genomic and chemical information
  3. Biological systems database KEGG
Selected publications
  1. Moriya, Y., Shigemizu, D., Hattori, M., Tokimatsu, T., Kotera, M., Goto, S., and Kanehisa, M., PathPred: an enzyme-catalyzed metabolic pathway prediction server. Nucleic Acids Res. 38, W138-W143 (2010)  [pubmed]
  2. Kanehisa, M., Goto, S., Furumichi, M., Tanabe, M., and Hirakawa, M., KEGG for representation and analysis of molecular networks involving diseases and drugs. Nucleic Acids Res. 38, D355-D360 (2010)  [pubmed]
  3. Shigemizu, D., Araki, M., Okuda, S., Goto, S., and Kanehisa, M., Extraction and analysis of chemical modification patterns in drug development. J Chem Inf Model 49, 1122-9 (2009)  [pubmed]
  4. Hashimoto, K., Tokimatsu, T., Kawano, S., Yoshizawa, A.C., Okuda, S., Goto, S., and Kanehisa, M., Comprehensive analysis of glycosyltransferases in eukaryotic genomes for structural and functional characterization of glycans. Carbohydr Res 344, 881-7 (2009)  [pubmed]
  5. Yamanishi, Y., Araki, M., Gutteridge, A., Honda, W., and Kanehisa, M., Prediction of drug-target interaction networks from the integration of chemical and genomic spaces. Bioinformatics 24, i232-i240 (2008).  [pubmed]
  6. Kanehisa, M., Araki, M., Goto, S., Hattori, M., Hirakawa, M., Itoh, M., Katayama, T., Kawashima, S., Okuda, S., Tokimatsu, T., and Yamanishi, Y., KEGG for linking genomes to life and the environment. Nucleic Acids Res. 36, D480-D484 (2008).  [pubmed]
  7. Hashimoto, K., Yoshizawa, A.C., Okuda, S., Kuma, K., Goto, S., and Kanehisa, M., The repertoire of desaturases and elongases reveals fatty acid variations in 56 eukaryotic genomes. J. Lipid Res. 49, 183-191 (2008).  [pubmed]
  8. Limviphuvadh, V., Tanaka, S., Goto, S., Ueda, K., and Kanehisa, M., The commonality of protein interaction networks determined in Neurodegenerative disorders (NDDs). Bioinformatics 23, 2129-2138 (2007).  [pubmed]
  9. Oh, M., Yamada, T., Hattori, M., Goto, S., and Kanehisa, M., Systematic analysis of enzyme-catalyzed reaction patterns and prediction of microbial biodegradation pathways. J. Chem. Inf. Model. 47, 1702-1712 (2007).  [pubmed]
  10. Minowa, Y., Araki, M., and Kanehisa, M., Comprehensive analysis of distinctive polyketide and nonribosomal peptide structural motifs encoded in microbial genomes. J. Mol. Biol. 368, 1500-1517 (2007).  [pubmed]
  11. Hashimoto, K., Goto, S., Kawano, S., Aoki-Kinoshita, K.F., Ueda, N., Hamajima, M., Kawasaki, T., and Kanehisa, M., KEGG as a glycome informatics resource. Glycobiology 16, 63R-70R (2006).  [pubmed]
  12. Kanehisa, M., Goto, S., Hattori, M., Aoki-Kinoshita, K.F., Itoh, M., Kawashima, S., Katayama, T., Araki, M., and Hirakawa, M., From genomics to chemical genomics: new developments in KEGG. Nucleic Acids Res. 34, D354-D357 (2006).  [pubmed]
  13. Kawano, S., Hashimoto, K., Miyama, T., Goto, S., and Kanehisa, M., Prediction of glycan structures from gene expression data based on glycosyltransferase reactions. Bioinformatics 21, 3976-3982 (2005).  [pubmed]
  14. Yamanishi, Y., Vert, J.-P., and Kanehisa, M., Supervised enzyme network inference from the integration of genomic data and chemical information. Bioinformatics 21, i468-i477 (2005).  [pubmed]
  15. Kotera, M., Okuno, Y., Hattori, M., Goto, S., and Kanehisa, M., Computational assignment of the EC numbers for genomic-scale analysis of enzymatic reactions. J. Am. Chem. Soc. 126, 16487-16498 (2004).  [pubmed]
  16. Igarashi, Y., Aoki, K.F., Mamitsuka, H., Kuma, K., and Kanehisa, M., The evolutionary repertoires of the eukaryotic-type ABC transporters in terms of the phylogeny of ATP-binding domains in eukaryotes and prokaryotes. Mol. Biol. Evol. 21, 2149-2160 (2004).  [pubmed]
  17. Hattori, M., Okuno, Y., Goto, S., and Kanehisa, M., Development of a chemical structure comparison method for integrated analysis of chemical and genomic information in the metabolic pathways. J. Am. Chem. Soc. 125, 11853-11856 (2003).  [pubmed]
  18. Kanehisa, M. and Bork, P., Bioinformatics in the post-sequence era. Nature Genetics 33, 305-310 (2003).  [pubmed]
  19. Kanehisa, M., "Post-genome Informatcs" Oxford University Press, Oxford (2000)

Update: May 07,2012