Academic career
| 1994.3 | Graduated from Dr. Course, Kyushu University
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| 1994.3 | D. Eng., Kyushu University
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| 1994.4-1999.9 | Research Associate, Kyoto University
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| 1999.10- | Associate Professor, Kyoto University |
Research field
Current research
- Development of a database for chemical compounds and reactions in biological pathways
- Development of a database for link information among databases
- Prediction of molecular interaction and functional association networks
- Development of a database of antigenic variations for the elucidation of their evolutionary and functional mechanisms
Selected publications
- Kanehisa M, Goto S, Sato Y, Furumichi M, Tanabe M., KEGG for integration and interpretation of large-scale molecular data sets. Nucleic Acids Res 40, D109-14 (2012) [pubmed]
- Kotera M, Tokimatsu T, Kanehisa M, Goto S., MUCHA: multiple chemical alignment algorithm to identify building block substructures of orphan secondary metabolites. BMC Bioinformatics 12 Suppl 14, S1 (2011) [pubmed]
- Takarabe M, Shigemizu D, Kotera M, Goto S, Kanehisa M., Network-based analysis and characterization of adverse drug-drug interactions. J Chem Inf Model 51, 2977-85 (2011) [pubmed]
- Hattori M, Tanaka N, Kanehisa M, Goto S., SIMCOMP/SUBCOMP: chemical structure search servers for network analyses. Nucleic Acids Res 38, W652-6 (2010) [pubmed]
- Moriya Y, Shigemizu D, Hattori M, Tokimatsu T, Kotera M, Goto S, Kanehisa M., PathPred: an enzyme-catalyzed metabolic pathway prediction server. Nucleic Acids Res 38, W138-43 (2010) [pubmed]
- Yamanishi Y, Kotera M, Kanehisa M, Goto S., Drug-target interaction prediction from chemical, genomic and pharmacological data in an integrated framework. Bioinformatics 26, i246-54 (2010) [pubmed]
- Wheelock CE, Wheelock AM, Kawashima S, Diez D, Kanehisa M, van Erk M, Kleemann R, Haeggstrom JZ, Goto S., Systems biology approaches and pathway tools for investigating cardiovascular disease. Mol Biosyst 5, 588-602 (2009). [pubmed]
- Hayes CN, Diez D, Joannin N, Honda W, Kanehisa M, Wahlgren M, Wheelock CE, Goto S., varDB: a pathogen-specific sequence database of protein families involved in antigenic variation. Bioinformatics 24, 2564-5 (2008) [pubmed]
- Kanehisa M, Araki M, Goto S, Hattori M, Hirakawa M, Itoh M, Katayama T, Kawashima S, Okuda S, Tokimatsu T, Yamanishi Y., KEGG for linking genomes to life and the environment. Nucleic Acids Res 36, D480-4 (2008) [pubmed]
- Itoh M, Nacher JC, Kuma K, Goto S, Kanehisa M., Evolutionary history and functional implications of protein domains and their combinations in eukaryotes. Genome Biol 8, R121 (2007) [pubmed]
- Gutteridge A, Kanehisa M, Goto S., Regulation of metabolic networks by small molecule metabolites. BMC Bioinformatics 8, 88 (2007) [pubmed]
- Okuda S, Kawashima S, Kobayashi K, Ogasawara N, Kanehisa M, Goto S., Characterization of relationships between transcriptional units and operon structures in Bacillus subtilis and Escherichia coli. BMC Genomics 8, 48 (2007) [pubmed]
- Masoudi-Nejad A, Tonomura K, Kawashima S, Moriya Y, Suzuki M, Itoh M, Kanehisa M, Endo T, Goto S., EGassembler: online bioinformatics service for large-scale processing, clustering and assembling ESTs and genomic DNA fragments. Nucleic Acids Res 34, W459-62 (2006) [pubmed]
- Yamada T, Kanehisa M, Goto S., Extraction of phylogenetic network modules from the metabolic network. BMC Bioinformatics 7, 130 (2006). [pubmed]
- Goto S, Okuno Y, Hattori M, Nishioka T, Kanehisa M, LIGAND: database of chemical compounds and reactions in biological pathways Nucleic Acids Res 30, 402-404 (2002). [pubmed]
- Kanehisa M, Goto S., KEGG: Kyoto Encyclopedia of Genes and Genomes. Nucleic Acids Res 28, 27-30 (2000). [pubmed]
- Goto S, Nishioka T, Kanehisa M., LIGAND: chemical database for enzyme reactions. Bioinformatics 14, 591-599 (1998). [pubmed]
- Goto S, Bono H, Ogata H, Fujibuchi W, Nishioka T, Sato K, Kanehisa M., Organizing and computing metabolic pathway data in terms of binary relations. Pac Symp Biocomput 2, 175-86 (1997). [pubmed]
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