Faculty Information, Institute for Chemical Research, Kyoto University   [ English | Japanese ]


GOTO, Susumu

Bioinformatics Center - Chemical Life Science -
Associate Professor
D. Eng
URL:http://goto.kuicr.kyoto-u.ac.jp/
E-mail: goto@kuicr.kyoto-u.ac.jp
Tel: 0774-38-3271
Fax: 0774-38-3269
Academic career
    1994.3 Graduated from Dr. Course, Kyushu University
    1994.3 D. Eng., Kyushu University
    1994.4-1999.9 Research Associate, Kyoto University
    1999.10- Associate Professor, Kyoto University
Research field
    Bioinformatics
Current research
  1. Development of a database for chemical compounds and reactions in biological pathways
  2. Development of a database for link information among databases
  3. Prediction of molecular interaction and functional association networks
  4. Development of a database of antigenic variations for the elucidation of their evolutionary and functional mechanisms
Selected publications
  1. Kotera M, Yamanishi Y, Moriya Y, Kanehisa M, Goto S., GENIES: gene network inference engine based on supervised analysis. Nucleic Acids Res 40, W162-7 (2012)  [pubmed]
  2. Kanehisa M, Goto S, Sato Y, Furumichi M, Tanabe M., KEGG for integration and interpretation of large-scale molecular data sets. Nucleic Acids Res 40, D109-14 (2012)  [pubmed]
  3. Kotera M, Tokimatsu T, Kanehisa M, Goto S., MUCHA: multiple chemical alignment algorithm to identify building block substructures of orphan secondary metabolites. BMC Bioinformatics 12 Suppl 14, S1 (2011)  [pubmed]
  4. Diez D, Hayes N, Joannin N, Normark J, Kanehisa M, Wahlgren M, Wheelock CE, Goto S., varDB: a database of antigenic variant sequences--current status and future prospects. Acta Trop 114, 144-51 (2010)  [pubmed]
  5. Hattori M, Tanaka N, Kanehisa M, Goto S., SIMCOMP/SUBCOMP: chemical structure search servers for network analyses. Nucleic Acids Res 38, W652-6 (2010)  [pubmed]
  6. Yamanishi Y, Kotera M, Kanehisa M, Goto S., Drug-target interaction prediction from chemical, genomic and pharmacological data in an integrated framework. Bioinformatics 26, i246-54 (2010)  [pubmed]
  7. Wheelock CE, Wheelock AM, Kawashima S, Diez D, Kanehisa M, van Erk M, Kleemann R, Haeggstrom JZ, Goto S., Systems biology approaches and pathway tools for investigating cardiovascular disease. Mol Biosyst 5, 588-602 (2009).  [pubmed]
  8. Hayes CN, Diez D, Joannin N, Honda W, Kanehisa M, Wahlgren M, Wheelock CE, Goto S., varDB: a pathogen-specific sequence database of protein families involved in antigenic variation. Bioinformatics 24, 2564-5 (2008)  [pubmed]
  9. Gutteridge A, Kanehisa M, Goto S., Regulation of metabolic networks by small molecule metabolites. BMC Bioinformatics 8, 88 (2007)  [pubmed]
  10. Okuda S, Kawashima S, Kobayashi K, Ogasawara N, Kanehisa M, Goto S., Characterization of relationships between transcriptional units and operon structures in Bacillus subtilis and Escherichia coli. BMC Genomics 8, 48 (2007)  [pubmed]
  11. Masoudi-Nejad A, Tonomura K, Kawashima S, Moriya Y, Suzuki M, Itoh M, Kanehisa M, Endo T, Goto S., EGassembler: online bioinformatics service for large-scale processing, clustering and assembling ESTs and genomic DNA fragments. Nucleic Acids Res 34, W459-62 (2006)  [pubmed]
  12. Yamada T, Kanehisa M, Goto S., Extraction of phylogenetic network modules from the metabolic network. BMC Bioinformatics 7, 130 (2006).  [pubmed]
  13. Goto S, Okuno Y, Hattori M, Nishioka T, Kanehisa M, LIGAND: database of chemical compounds and reactions in biological pathways Nucleic Acids Res 30, 402-404 (2002).  [pubmed]
  14. Kanehisa M, Goto S., KEGG: Kyoto Encyclopedia of Genes and Genomes. Nucleic Acids Res 28, 27-30 (2000).  [pubmed]
  15. Goto S, Nishioka T, Kanehisa M., LIGAND: chemical database for enzyme reactions. Bioinformatics 14, 591-599 (1998).  [pubmed]
  16. Goto S, Bono H, Ogata H, Fujibuchi W, Nishioka T, Sato K, Kanehisa M., Organizing and computing metabolic pathway data in terms of binary relations. Pac Symp Biocomput 2, 175-86 (1997).  [pubmed]

Update: Apr 24,2013