Faculty Information, Institute for Chemical Research, Kyoto University   [ English | Japanese ]


FUJII, Tomomi

Advanced Research Center for Beam Science - Structural Molecular Biology -
Assistant Professor
Doctor of Philosophy (Science)
URL:
E-mail: fujii　@　scl.kyoto-u.ac.jp
Tel: 0774-38-3258
Fax: 0774-38-3045
Academic career
    1993.7 Left from Dr. Course, Tokyo Institute of Technology
    1993.8 - Assistant Professor, Kyoto University
    1998.3 Ph.D. (Sci.), Tokyo Institute of Technology
Research field
    Structural Biology, Protein Crystallography
Current research
  1. Structural Biology of Protein Functions
  2. Structural Basis in Reaction Mechanism of Enzymes
  3. Structural Study for Thermostability of Protein Molecules
Selected publications
  1. Fujii T, Goda Y, Yoshida M, Oikawa T, Hata Y., Crystallization and preliminary X-ray diffraction studies of maleylacetate reductase from Rhizobium sp. strain MTP-10005. Acta Crystallogr Sect F Struct Biol Cryst Commun 64, 737-9 (2008)  [pubmed]
  2. Fujii T, Oikawa T, Muraoka I, Soda K, Hata Y., Crystallization and preliminary X-ray diffraction studies of tetrameric malate dehydrogenase from the novel Antarctic psychrophile Flavobacterium frigidimaris KUC-1. Acta Crystallogr Sect F Struct Biol Cryst Commun 63, 983-6 (2007)  [pubmed]
  3. Mima J, Hayashida M, Fujii T, Narita Y, Hayashi R, Ueda M, Hata Y, Structure of the Carboxypeptidase Y Inhibitor Ic in Complex with the Cognate Proteinase Reveals a Novel Mode of the Proteinase-Protein Inhibitor Interaction J. Mol. Biol. 346, 1323-1334 (2005)
  4. Fujii T, Hayashida M, Hamasu M, Ishiguro M, Hata Y, Structures of Two Lectins from the Roots of Pokeweed (Phytolacca americana) Acta Cryst. D60, 665-673 (2004).
  5. Fujii T, Sakai H, Kawata Y, Hata Y, Crystal Structure of Thermostable Aspartasae from Bacillus sp. YM55-1: Structure-based Exploration of Functional Sites in the Aspartase Family J. Mol. Biol. 328, 635-654 (2003)
  6. Hayashida M, Fujii T, Hamasu M, Ishiguro M, Hata Y, Similarity between Protein-Protein and Protein-Carbohydrate Interactions, Revealed by Two Crystal Structures of Lectins from the Roots of Pokeweed J. Mol. Biol. 334, 551-565 (2003)
  7. Mihara H, Fujii T, Kato S, Kurihara T, Hata Y, Esaki N, Structure of External Aldimine of Escherichia coli CsdB, an IscS/NifS Homolog: Implications for Its Specificity toward Selenocysteine J. Biochem. 131, 679-685 (2002)
  8. Fujii T, Maeda M, Mihara H, Kurihara T, Esaki N, Hata Y, Structure of a NifS Homologue: X-ray Structure Analysis of CsdB, an Escherichia coli Counterpart of Mammalian Selenocysteine Lyase Biochemistry 39, 1263-1273 (2000).
  9. Li Y F, Hata Y, Fujii T, Hisano T, Nishihara M, Kurihara T, Esaki N, Structure of Reaction Intermediates of L-2-Haloacid Dehalogenase and Implications for the Reaction Mechanism J. Biol. Chem. 273, 15035-15044 (1998).
  10. Li Y F, Hata Y, Fujii T, Kurihara T, Esaki N, X-Ray Structure of a Reaction Intermediate of L-2-Haloacid Dehalogenase with L-2-Chloropropionamide J. Biochem. 124, 20-22 (1998).
  11. Fujii T, Hata Y, Oozeki M, Moriyama H, Wakagi T, Tanaka N, Oshima T, The Crystal Structure of Zinc-Containing Ferredoxin from the Thermoacidphilic Archaeon Sulfolobus sp. Strain 7 Biochemistry 36, 1505-1513 (1997).
  12. Hisano T, Hata Y, Fujii T, Liu J Q, Kurihara T, Esaki N, Soda K, Crystal Structure of L-2-Haloacid Dehalogenase from Pseudomonas sp. YL. Anα/β hydrolase structure that is different from theα/β hydrolase fold J. Biol. Chem. 271, 20322-20330 (1996).
  13. Fujii T, Hata Y, Wakagi T, Tanaka N, Oshima T, Novel Zinc-binding Centre in Thermoacidophilic Archaeal Ferredoxins Nature Struct. Biol. 3, 834-837 (1996).
  14. Miyatake H, Hata Y, Fujii T, Hamada K, Morihara K, Katsube Y, Crystal Structure of the Unliganded Alkaline Proterase from Pseudomonas aeruginosa IFO3080 and Its Conformational Changes on Ligand Binding J. Biochem. 118, 474-479 (1995).

Update: Nov 15,2012