Faculty Information, Institute for Chemical Research, Kyoto University   [ English | Japanese ]


Bioinformatics Center - Chemical Life Science -
(Laboratory in the Graduate school of Science, Graduate school of Pharmacology)
Assistant Professor
Dr. Sc.
E-mail: roblanc@kuicr.kyoto-u.ac.jp
Tel: 0774-38-3296
Fax: 0774-38-3269

Academic career
    2010.10 PhD student CNRS (France)
    2014.1 Postdoc INRA (France)
    2015.8 Assistant Professor at Kyoto University (Japan)
Research field
    Despite the importance of microbial communities for the functioning of ecosystems, little is known about their diversity and functioning and how it varies in time and space. In addition, mechanisms shaping this diversity and the interactions between the various members of these communities are poorly known. This lack of knowledge is especially true for the eukaryotic component and their associated viruses, both in marine and continental environments. In this context, I am interested in the diversity, evolution, and ecology of the eukaryotic component of planktonic communities and their viruses. I seek answers to questions such as: What is the within-species genetic diversity in planktonic organisms? What shapes this variation? What is the diversity of eukaryotic virus in oceans and what are their ecological roles? -Thematic: Population genomics (intraspecific diversity of eukaryotic plankton) – Environmental genomics (diversity, evolution and ecological role of eukaryotic viruses) – Evolutionary genomic (Evolution of duplicated genes) -Keywords: evolution, diversity, genomic, plankton, viruses.
Current research
  1. Assessing the diversity and deciphering the roles of marine eukaryotic viruses in epipelagic oceans using environmental genomics and contextual data.
  2. Understanding the evolutionary history of large nucleocytoplasmic DNA viruses via genomic analysis of in-lab isolated viruses.
  3. Study of standing genomic variation in phytoplankton species such as Ostreococcus tauri or Triparma laevis: what mechanisms shape this variation and how this variation channels future evolutionary changes?
  4. During my postdoc I worked on “evolution by gene duplication” in Meloidogyne (nematodes). I continue to work on this thematic in land plants where I try to understand the processes that led to functional diversification of their phosphatidylinositol phosphate 5-kinases.
Selected publications
  1. Yoshikawa G, Askora A, Blanc-Mathieu R, Kawasaki T, Li Y, Nakano M, Ogata H, and Yamada T., Xanthomonas citri jumbo phage XacN1 exhibits a wide host range and high complement of tRNA genes. Sci. Rep. 8, 4486 (2018)  [pubmed]
  2. Carradec Q, Pelletier E, Da Silva C, Alberti A, Seeleuthner Y, Blanc-Mathieu R, Lima-Mendez G, Rocha F, Tirichine L, Labadie K, Kirilovsky A, Bertrand A, Engelen S, Madoui MA, Méheust R, Poulain J, Romac S, Richter DJ, Yoshikawa G, Dimier C, Kandels-Lewis S, Picheral M, Searson S; Tara Oceans Coordinators, Jaillon O, Aury JM, Karsenti E, Sullivan MB, Sunagawa S, Bork P, Not F, Hingamp P, Raes J, Guidi L, Ogata H, de Vargas C, Iudicone D, Bowler C, Wincker P., A global ocean atlas of eukaryotic genes. Nat Commun. 9, 373 (2018)  [pubmed]
  3. Blanc-Mathieu R, Krasovec M, Hebrard M, Yau S, Desgranges E, Martin J, Schackwitz W, Kuo A, Salin G, Donnadieu C, Desdevises Y, Sanchez-Ferandin S, Moreau H, Rivals E, Grigoriev IV, Grimsley N, Eyre-Walker A, Piganeau G., Population genomics of picophytoplankton unveils novel chromosome hypervariability. Sci Adv. 3,e1700239 (2017)  [pubmed]
  4. Blanc-Mathieu R, Perfus-Barbeoch L, Aury JM, Da Rocha M, Gouzy J, Sallet E, Martin-Jimenez C, Bailly-Bechet M, Castagnone-Sereno P, Flot JF, Kozlowski DK, Cazareth J, Couloux A, Da Silva C, Guy J, Kim-Jo YJ, Rancurel C, Schiex T, Abad P, Wincker P, Danchin EGJ, Hybridization and polyploidy enable genomic plasticity without sex in the most devastating plant-parasitic nematodes. PLoS Genet. 13,e1006777 (2017)  [pubmed]
  5. Nishimura Y, Watai H, Honda T, Mihara T, Omae K, Roux S, Blanc-Mathieu R, Yamamoto K, Hingamp P, Sako Y, Sullivan MB, Goto S, Ogata H, Yoshida T, Environmental Viral Genomes Shed New Light on Virus-Host Interactions in the Ocean. mSphere 2,e00359-16 (2017)  [pubmed]
  6. Bhunchoth A, Blanc-Mathieu R, Mihara T, Nishimura Y, Askora A, Phironrit N, Leksomboon C, Chatchawankanphanich O, Kawasaki T, Nakano M, Fujie M, Ogata H, Yamada T., Two asian jumbo phages, ϕRSL2 and ϕRSF1, infect Ralstonia solanacearum and show common features of ϕKZ-related phages. Virology 494, 56-66 (2016)  [pubmed]
  7. Blanc-Mathieu R, Ogata H., DNA repair genes in the Megavirales pangenome. Curr. Opin. Microbiol. 31, 94-100 (2016)  [pubmed]
  8. Blanc-Mathieu R, Verhelst B, Derelle E, Rombauts S, Bouget FY, Carre I, Chateau A, Eyre-Walker A, Grimsley N, Moreau H, Piegu B, Rivals E, Schackwitz W, Van de Peer Y, Piganeau G., An improved genome of the model marine alga Ostreococcus tauri unfolds by assessing Illumina de novo assemblies. BMC Genomics 15, 1103 (2014)  [pubmed]
  9. Blanc-Mathieu R, Sanchez-Ferandin S, Eyre-Walker A, Piganeau G., Organellar inheritance in the green lineage: insights from Ostreococcus tauri. Genome Biol. Evol. 5, 1503-11 (2013)  [pubmed]
  10. Marcombe S, Blanc-Mathieu R, Pocquet N, Riaz MA, Poupardin R, Selior S, Darriet F, Reynaud S, Yebakima A, Corbel V, David JP, Chandre F., Insecticide resistance in the dengue vector Aedes aegypti from Martinique: distribution, mechanisms and relations with environmental factors. PLoS One 7, e30989 (2012)  [pubmed]
  11. Toulza E, Blanc-Mathieu R, Gourbiere S and Piganeau G, Environmental and Evolutionary Genomics of Microbial Algae: Power and Challenges of Metagenomics. Chapter in ADVANCES IN BOTANICAL RESEARCH (2012)

Update: Jul 20,2018